Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens
نویسندگان
چکیده
منابع مشابه
Microbial degradation of steroidal estrogens.
Steroidal estrogens, widespread in the environment, are contaminants of potential concern because exposure to these compounds can cause adverse impacts on aquatic life. Intensive research efforts have been undertaken in order to better understand the environmental occurrence of these compounds. In addition to physical/chemical reactions, biological processes - microbial biodegradation of steroi...
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Alcoholic beverages contain not only alcohol but also numerous other substances (i.e., congeners) that may contribute to the beverages' physiological effects. Plants used to produce alcoholic beverages contain estrogenlike substances (i.e., phytoestrogens). Observations that men with alcoholic cirrhosis often show testicular failure and symptoms of feminization have suggested that alcoholic bev...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2019
ISSN: 0021-9258
DOI: 10.1074/jbc.ra119.010950